PROGNOSTIC IMPACT OF REDUCED HER2 PROTEIN EXPRESSION IN POST-NEOADJUVANT THERAPY RESECTION SPECIMENS: A SINGLE INSTITUTION EXPERIENCE AND REVIEW OF THE LITERATURE

Background: Retesting for Human epidermal growth factor receptor-2 (HER2) in post-neoadjuvant therapy resection is variable, and data is conflicting regarding the prognostic significance of changes in HER2 expression pre and post therapy.Methods: We identified 104 patients with localized HER2 IHC 3+ breast cancer who received neoadjuvant trastuzuma

Background: Scoliosis and limb length discrepancy are the major orthopaedic abnormalities in patients with Silver-Russel syndrome (SRS).In this paper, we describe Diaper Sets a series of orthopaedic interventions in an attempt to overcome the progressive pathologic mechanism in a 7-year-old girl who manifested the full phenotypic features of SRS.Ma

Introduction: Evaluating the needs of People Living with HIV / AIDS (PLHA) and providing them with adequate care and support is important in combating the Acquired Immunodeficiency Syndrome (AIDS) epidemic.Objectives: The study was conducted to ascertain the needs of PLHA, the support obtained and required, extent of involvement in programs related

Physical-approach-based wind forecasts have the merit of a heavily reduced uncertainty in predictions, but very often suffer from a prohibitively lengthy numerical computation time, if high spatial resolutions are Basketball required.To tackle this hurdle, proper orthogonal decomposition (POD) has manifested extraordinary power in reducing the numb

Kwang-Ho Cha,1,3 Kyung-Jin Cho,3 Min-Soo Kim,4 Jeong-Soo Kim,3 Hee Jun Park,1,3 Junsung Park,1,3 Wonkyung Cho,1,3 Jeong-Sook Park,3 Sung-Joo Hwang1,21Yonsei Institute of Pharmaceutical Sciences, 2College of Pharmacy, Yonsei University, Incheon, Republic of Korea; 3College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea; 4Depar